(S)-Amlodipine Besylate (103129-82-4(free base))
CAS No.
(S)-Amlodipine Besylate (103129-82-4(free base)) ( —— )
产品货号. M19310 CAS No.
Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication.
纯度: 98%
规格 | 价格/人民币 | 库存 | 数量 |
生物学信息
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产品名称(S)-Amlodipine Besylate (103129-82-4(free base))
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication.
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产品描述Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however, with differing nomenclature. As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity.
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同义词——
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体Calcium channel
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研究领域——
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适应症——
化学信息
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CAS Number--
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分子量567.05
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分子式C26H31ClN2O8S
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纯度98%
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溶解度——
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SMILESCCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Velusetrag hydrochlo...
Velusetrag (TD-5108) is a potent, selective and oral 5-HT4 receptor agonist with pKi of 7.7, shows >500-fold selectivity over other 5-HT receptors.
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RU 24969 hemisuccina...
RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.
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PRX-07034
PRX-07034 is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents.?PRX-07034 is both a potent (Ki = 4-8 nM) and highly selective 5-HT(6) receptor antagonist (≥100-fold selectivity for the 5-HT(6) receptor compared to 68 other GPCRs, ion channels, and transporters, except D(3) (Ki = 71 nM) and 5-HT(1B) (Ki = 260 nM) receptors.